Author Question: What therapy has been proven to improve survival in patients with COPD and pulmonary hyper-tension? ... (Read 37 times)

RYAN BANYAN · **on:** Jul 16, 2018

What therapy has been proven to improve survival in patients with COPD and pulmonary hyper-tension?

a. Bronchodilators
b. Oral vasodilators
c. Oxygen
d. Prostanoids

Question 2

What is the most important factor contributing to the onset of pulmonary hypertension in the pa-tient with COPD?

a. Alveolar hypoxia
b. Compression of pulmonary vasculature
c. Left ventricular failure
d. Loss of vascular surface

babybsemail · **Reply #1 on:** Jul 16, 2018

Answer to Question 1

ANS: C
Oxygen therapy is the main treatment that improves survival among patients with COPD and pulmonary hypertension, though smoking cessation and lung volume reduction (in selected indi-viduals) may also confer survival benefits in patients with COPD.

Answer to Question 2

ANS: A
Alveolar hypoxia, because of its potent pulmonary vasoconstrictive effect, is probably the most important factor contributing to pulmonary hypertension in patients with COPD. Sustained alve-olar hypoxia causes pulmonary vasoconstriction and eventually medial hypertrophy, fibrosis of the intima, and narrowing of the lumen of the pulmonary blood vessels.