Author Question: What type of drug is Bosentan? a. Corticosteroid b. Endothelin antagonists c. Phosphodiesterase ... (Read 71 times)

eruditmonkey@yahoo.com · **on:** Jul 16, 2018

What type of drug is Bosentan?

a. Corticosteroid
b. Endothelin antagonists
c. Phosphodiesterase inhibitors
d. Prostanoids

Question 2

What ECG finding is most often associated with right-sided heart failure and pulmonary hyper-tension?

a. Elevated ST segment
b. Inverted P wave in lead I
c. Prolonged PR interval
d. Right-axis deviation

aidanmbrowne · **Reply #1 on:** Jul 16, 2018

Answer to Question 1

ANS: B
Endothelin antagonists represent another class of medications that are newly available for treat-ing pulmonary hypertension. Bosentan, an orally administered endothelin receptor antagonist, improves walking distance, hemodynamic variables, and functional class in patients with PAH.

Answer to Question 2

ANS: D
ECG findings usually include right-axis deviation, right ventricular hypertrophy, and strain. The echocardiogram may show dilatation of the right ventricle and right atrium and tricuspid regur-gitation.