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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.