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Author Question: A nurse administers medications to four patients with Alzheimer's disease. Which medication would be ... (Read 109 times)

folubunmi

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on: Jul 19, 2018
A nurse administers medications to four patients with Alzheimer's disease. Which medication would be expected to antagonize N-methyl-D-aspartate (NMDA) channels rather than cholinesterase?
 
  a. donepezil (Aricept)
  b. rivastigmine (Exelon)
  c. memantine (Namenda)
  d. galantamine (Razadyne)

Question 2

Consider these problems: apolipoprotein E (apoE) malfunction, neuritic plaques, neurofibrillary tangles, granulovascular degeneration, and brain atrophy. Which condition corresponds to this group?
 
  a. Alzheimer's disease
  b. Acquired immunodeficiency syndrome (AIDS)related dementia
  c. Wernicke's encephalopathy
  d. Central anticholinergic syndrome


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tofugiraffe

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Reply #1 on: Jul 19, 2018
Answer to Question 1

ANS: C
Memantine blocks the NMDA channels and is used in moderate-to-late stages of the disease. Donepezil, rivastigmine, and galantamine are all cholinesterase inhibitors. These drugs increase the availability of acetylcholine and are most often used to treat mild-to-moderate Alzheimer's disease.

Answer to Question 2

ANS: A
The problems are all aspects of the pathophysiologic characteristics of Alzheimer's disease.


folubunmi

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Reply #2 on: Jul 19, 2018
TY


tofugiraffe

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Reply #3 on: Jul 19, 2018
Happy to Help


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