What is the role of blood-brain barrier (BBB) transporters in ...

[Chloeellawright]

What is the role of blood-brain barrier (BBB) transporters in neurotransmission?
 
  1. Facilitate medication absorption.
  2. Increase neurotransmission activity.
  3. Shuttle neurotransmitters away from the brain.
  4. Maintain a steady state of available medication molecules.

Question 2

A patient who has been prescribed a selective serotonin-reuptake inhibitor (SSRI) asks the nurse how it works. What is the best response by the nurse?
 
  1. SSRIs maintain the drug in its bound form, allowing more of the drug to attach to the neurotransmitter.
  2. SSRIs increase enzymatic action in the blood-brain barrier.
  3. SSRIs improve acid-base balance, enhancing the penetration of the blood-brain barrier.
  4. SSRIs target blood-brain barrier transporters and prevent the reuptake of the neurotransmitter.

[Melissahxx]

Answer to Question 1

Answer: 3
Explanation: BBB transporters shuttle away neurotransmitters and their metabolites to prevent them from entering the brain. BBB transporters are not involved in increasing neurotransmission, facilitating absorption, or maintaining a steady state of available medication levels in the blood.

Answer to Question 2

Answer: 4
Explanation: Selective serotonin reuptake inhibitors (SSRIs) stop the reuptake of the neurotransmitter, making more neurotransmitter available for the receptors on the postsynaptic neuron. SSRIs are not involved in enhancing enzymatic activity, maintaining drugs in their bound form, or improving acid-base balance.