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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Less than one of every three adults with high LDL cholesterol has the condition under control. Only 48.1% with the condition are being treated for it.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.