A patient is receiving cidofovir (Vistide) as part
of treatment for a viral infection, and the nurse is preparing to administer probenecid, which is also ordered. Which is the rationale for administering probenecid along with the cidofovir treatment?
a. Probenecid has a synergistic effect when given with cidofovir, thus making the antiviral medication more effective.
b. The probenecid also prevents replication of the virus.
c. Concurrent drug therapy with probenecid reduces the nephrotoxicity of the cidofovir.
d. The probenecid reduces the adverse gastrointestinal effects of the cidofovir.
Question 2
The nurse is administering intravenous acyclovir (Zovirax) to a patient with a viral infection. Which administration technique is correct?
a. Infuse intravenous acyclovir slowly, over at least 1 hour.
b. Infuse intravenous acyclovir by rapid bolus.
c. Refrigerate intravenous acyclovir.
d. Restrict oral fluids during intravenous acyclovir therapy.
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