This topic contains a solution. Click here to go to the answer

Author Question: The patient is malnourished and has a low serum albumin. The physician has ordered aspirin, a highly ... (Read 58 times)

james

  • Hero Member
  • *****
  • Posts: 573
The patient is malnourished and has a low serum albumin. The physician has ordered aspirin, a highly protein-bound drug, for the patient. Which evaluation by the nurse best describes the effect this will have on the patient?
 
  1. The patient will be at risk to experience a decreased effectiveness of the drug.
  2. The patient will be at risk to experience toxic effects of the drug.
  3. The patient's kidneys will excrete the drug at a faster rate.
  4. The patient's serum globulin is more important than serum albumin.

Question 2

The patient has meningitis. The physician initially prescribed a water-soluble drug. Another physician changed the order to a lipid-soluble drug. The patient is confused about this. Which plan best resolves the patient's concern?
 
  1. Teach the patient that lipid-soluble drugs are better because of protein binding.
  2. Teach the patient that lipid-soluble drugs are more effective in treating his illness.
  3. Teach the patient that lipid-soluble drugs are better because they have fewer side effects.
  4. Teach the patient that lipid-soluble drugs are more effective because they are excreted at a slower rate.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

manuelcastillo

  • Sr. Member
  • ****
  • Posts: 304
Answer to Question 1

Correct Answer: 2
Rationale: Aspirin is a protein-bound drug. With a low albumin, there is less protein for aspirin to bind with, making more free drug available. There may be toxic, not decreased, effects from the drug because there is less protein for aspirin to bind with and more free drug available. The kidney will not be able to balance the amount of the drug and excrete it at a faster rate. Serum albumin plays a major role, more than serum globulin.

Answer to Question 2

Correct Answer: 2
Rationale: Drug molecules that are lipid soluble will usually pass through plasma membranes by simple diffusion and more easily reach their target cells. Lipid-soluble drugs do not necessarily have fewer side effects. Not all lipid-soluble drugs are protein bound. Lipid solubility does not affect drug excretion.





 

Did you know?

A recent study has found that following a diet rich in berries may slow down the aging process of the brain. This diet apparently helps to keep dopamine levels much higher than are seen in normal individuals who do not eat berries as a regular part of their diet as they enter their later years.

Did you know?

The longest a person has survived after a heart transplant is 24 years.

Did you know?

In inpatient settings, adverse drug events account for an estimated one in three of all hospital adverse events. They affect approximately 2 million hospital stays every year, and prolong hospital stays by between one and five days.

Did you know?

There can actually be a 25-hour time difference between certain locations in the world. The International Date Line passes between the islands of Samoa and American Samoa. It is not a straight line, but "zig-zags" around various island chains. Therefore, Samoa and nearby islands have one date, while American Samoa and nearby islands are one day behind. Daylight saving time is used in some islands, but not in others—further shifting the hours out of sync with natural time.

Did you know?

When Gabriel Fahrenheit invented the first mercury thermometer, he called "zero degrees" the lowest temperature he was able to attain with a mixture of ice and salt. For the upper point of his scale, he used 96°, which he measured as normal human body temperature (we know it to be 98.6° today because of more accurate thermometers).

For a complete list of videos, visit our video library