Author Question: Which of the following may cause cross-sensitivity in the patient who is receiving epoetin alfa ... (Read 86 times)

Haya94 · **on:** Jul 23, 2018

Which of the following may cause cross-sensitivity in the patient who is receiving epoetin alfa (Epogen)?

a. Albumin
b. Lactose
c. Nitrates
d. Synthetic insulin

Question 2

The patient has been placed on deferoxamine (Deseral) therapy. Which adverse effect of the drug must the health care provider monitor closely for, to prevent death of the patient?

a. Red discoloration of the urine
b. Proliferation of specific organisms leading to infection
c. Ocular toxicity
d. Auditory neurotoxicity

mjenn52 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: A
Epoetin alfa is contraindicated for use in patients with hypersensitivity to albumin or mammalian cell-derived products, or in those with uncontrolled hypertension.

Answer to Question 2

ANS: B
Because deferoxamine is a naturally occurring iron siderophore (a molecule facilitating iron up-take), it acts as a growth factor for Yersinia and Rhizopus. In susceptible individuals, deferox-amine increases the proliferation and virulence of these organisms, resulting in severe, often fatal, infection.