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Author Question: A patient has been started on therapy with disopyramide (Norpace). For which of the following ... (Read 54 times)

TVarnum

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on: Jul 23, 2018
A patient has been started on therapy with disopyramide (Norpace). For which of the following adverse effects should the health care provider periodically assess the client?
 
  a. Dry mouth, constipation, urinary retention, and blurred vision
  b. Anorexia, nausea, vomiting, and headaches
  c. Urinary frequency, diarrhea, and abdominal cramping
  d. Hypertension, tachycardia, and diminished peripheral pulses

Question 2

Which of the following mechanisms is applicable to the antiarrhythmic activity of quinidine glu-conate (Quinaglute)?
 
  a. Increases conduction velocity in the Purkinje fibers
  b. Increases the rate of rise in phase 0 depolarization
  c. Blocks slow calcium channels and increases the reactivation rate
  d. Suppresses automaticity and prolongs refractory periods


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kthug

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Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: A
The most common adverse effects of disopyramide are anticholinergic effects. These would in-clude dry mouth, blurred vision, constipation, and urinary hesitation and retention.

Answer to Question 2

ANS: D
Class IA drugs, such as quinidine, tend to suppress automaticity by lowering the pacemaker po-tential needed to provoke spontaneous depolarization. Refractory periods are prolonged, and premature electrical stimulation is less likely to occur.


TVarnum

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Reply #2 on: Jul 23, 2018
Both answers were spot on, thank you once again


kthug

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Reply #3 on: Jul 23, 2018
Great! Please up vote :D


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