This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A female patient taking phenytoin (Dilantin) is considering becoming pregnant. Which of the ... (Read 116 times)

magmichele12

  • Hero Member
  • *****
  • Posts: 559
on: Jul 23, 2018
A female patient taking phenytoin (Dilantin) is considering becoming pregnant. Which of the following statements correctly describes distribution of the drug to the fetus?
 
  a. It crosses the placenta and enters breast milk.
  b. It crosses the placenta but does not enter breast milk.
  c. It does not cross the placenta but enters breast milk.
  d. It does not cross the placenta or enter breast milk.

Question 2

The patient has been placed on zolmitriptan (Zomig). Which of the following drugs should the patient avoid receiving concurrently?
 
  a. Macrolide antibiotics
  b. Beta blockers
  c. Calcium channel blockers
  d. Antihypertensives


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

ndhahbi

  • Sr. Member
  • ****
  • Posts: 390
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: A
The hydantoins cross the placenta and enter breast milk. Fetal hydantoin syndrome is possible with phenytoin, producing craniofacial abnormalities, congenital heart defects, and microcephaly, among other birth defects.

Answer to Question 2

ANS: A
Many drugs interact with triptans; the primary concern is sustained vasoconstriction and vaso-spasm leading to ischemia. These drugs include macrolide antibiotics, azole antifungal drugs, and ergotamine, caffeine, nefazodone, nelfinavir, ritonavir, and CYP 3A4 inhibitors.


magmichele12

  • Member
  • Posts: 559
Reply 2 on: Jul 23, 2018
:D TYSM

shailee

  • Member
  • Posts: 392
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

There are 60,000 miles of blood vessels in every adult human.

Did you know?

Limit intake of red meat and dairy products made with whole milk. Choose skim milk, low-fat or fat-free dairy products. Limit fried food. Use healthy oils when cooking.

Did you know?

In inpatient settings, adverse drug events account for an estimated one in three of all hospital adverse events. They affect approximately 2 million hospital stays every year, and prolong hospital stays by between one and five days.

Did you know?

About 80% of major fungal systemic infections are due to Candida albicans. Another form, Candida peritonitis, occurs most often in postoperative patients. A rare disease, Candida meningitis, may follow leukemia, kidney transplant, other immunosuppressed factors, or when suffering from Candida septicemia.

Did you know?

Every flu season is different, and even healthy people can get extremely sick from the flu, as well as spread it to others. The flu season can begin as early as October and last as late as May. Every person over six months of age should get an annual flu vaccine. The vaccine cannot cause you to get influenza, but in some seasons, may not be completely able to prevent you from acquiring influenza due to changes in causative viruses. The viruses in the flu shot are killed—there is no way they can give you the flu. Minor side effects include soreness, redness, or swelling where the shot was given. It is possible to develop a slight fever, and body aches, but these are simply signs that the body is responding to the vaccine and making itself ready to fight off the influenza virus should you come in contact with it.

Welwitschia-mirabilis-female Welwitschia-mirabilis-female
Female in Dominican Pod, 2005 Female in Dominican Pod, 2005
PET scan of the brain in a patient with Alzheimer’s disease. PET scan of the brain in a patient with Alzheimer’s disease.
Taking attendance in the genome Taking attendance in the genome
A patient with goiter due to iodine deficiency. A patient with goiter due to iodine deficiency.
Gingival enlargement in a patient taking nifedipine. Gingival enlargement in a patient taking nifedipine.
Video: Renin/Angiotensin (water gain from urine & Na ion and water reabsorption)

For a complete list of videos, visit our video library