This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Which of the following numbers could be the therapeutic index (TI) of a drug for which there is the ... (Read 35 times)

chads108

  • Hero Member
  • *****
  • Posts: 507
on: Jul 23, 2018
Which of the following numbers could be the therapeutic index (TI) of a drug for which there is the greatest possibility of toxicity?
 
  a. 2
  b. 1
  c. 5
  d. 10

Question 2

Which substance produces a response equal to or greater than the effects of an endogenous chemical in the body?
 
  a. Competitive inhibitor
  b. Noncompetitive inhibitor
  c. Antagonist
  d. Agonist


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

cuttiesgirl16

  • Sr. Member
  • ****
  • Posts: 345
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
A drug's TI expresses the relative safety of a drug. TI relates the dose of a drug required to pro-duce a desired effect to that producing an adverse or toxic response. Drugs with a high TI are said to be safe (i.e., to have a wide margin of safety). Those with a low TI are relatively unsafe and have the narrowest margin of safety, therefore the greatest possibility of toxicity.

Answer to Question 2

ANS: D
Agonists combine with receptors to initiate events; that is, they have intrinsic activity that is produced by two different mechanisms. Agonist I drugs bind to the same site as an endogenous substance (e.g., neurotransmitter) to produce a similar response. The response usually equals, or is greater than, that of the endogenous substance. Agonist II drugs bind to different extracellular sites, with no response produced solely in the presence of the agonist. However, an enhanced re-sponse is generated when an existing endogenous substance also binds to its site.


chads108

  • Member
  • Posts: 507
Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it

bulacsom

  • Member
  • Posts: 329
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

A recent study has found that following a diet rich in berries may slow down the aging process of the brain. This diet apparently helps to keep dopamine levels much higher than are seen in normal individuals who do not eat berries as a regular part of their diet as they enter their later years.

Did you know?

A strange skin disease referred to as Morgellons has occurred in the southern United States and in California. Symptoms include slowly healing sores, joint pain, persistent fatigue, and a sensation of things crawling through the skin. Another symptom is strange-looking, threadlike extrusions coming out of the skin.

Did you know?

The training of an anesthesiologist typically requires four years of college, 4 years of medical school, 1 year of internship, and 3 years of residency.

Did you know?

In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.

Did you know?

More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.

Therapeutic Communication Skills Therapeutic Communication Skills
Drug–Drug Interactions with Warfarin Drug–Drug Interactions with Warfarin
Liposomal amphotericin B: Drug molecules are embedded in the lipid bilayer. Liposomal amphotericin B: Drug molecules are embedded in the lipid bilayer.
Clinically Significant Drug-Drug Interactions in Dentistry Clinically Significant Drug-Drug Interactions in Dentistry
Pacific Decadal Oscillation: PDO index Pacific Decadal Oscillation: PDO index
How to calculate the gain and loss gene numbers with low bootstrap of phylogenetic tree? How to calculate the gain and loss gene numbers with low bootstrap of phylogenetic tree?
Video: Introduction to Autism

For a complete list of videos, visit our video library