This topic contains a solution. Click here to go to the answer

Author Question: Which of the following numbers could be the therapeutic index (TI) of a drug for which there is the ... (Read 68 times)

chads108

  • Hero Member
  • *****
  • Posts: 507
Which of the following numbers could be the therapeutic index (TI) of a drug for which there is the greatest possibility of toxicity?
 
  a. 2
  b. 1
  c. 5
  d. 10

Question 2

Which substance produces a response equal to or greater than the effects of an endogenous chemical in the body?
 
  a. Competitive inhibitor
  b. Noncompetitive inhibitor
  c. Antagonist
  d. Agonist



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

cuttiesgirl16

  • Sr. Member
  • ****
  • Posts: 345
Answer to Question 1

ANS: B
A drug's TI expresses the relative safety of a drug. TI relates the dose of a drug required to pro-duce a desired effect to that producing an adverse or toxic response. Drugs with a high TI are said to be safe (i.e., to have a wide margin of safety). Those with a low TI are relatively unsafe and have the narrowest margin of safety, therefore the greatest possibility of toxicity.

Answer to Question 2

ANS: D
Agonists combine with receptors to initiate events; that is, they have intrinsic activity that is produced by two different mechanisms. Agonist I drugs bind to the same site as an endogenous substance (e.g., neurotransmitter) to produce a similar response. The response usually equals, or is greater than, that of the endogenous substance. Agonist II drugs bind to different extracellular sites, with no response produced solely in the presence of the agonist. However, an enhanced re-sponse is generated when an existing endogenous substance also binds to its site.




chads108

  • Member
  • Posts: 507
Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it


DylanD1323

  • Member
  • Posts: 314
Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

 

Did you know?

All adverse reactions are commonly charted in red ink in the patient's record and usually are noted on the front of the chart. Failure to follow correct documentation procedures may result in malpractice lawsuits.

Did you know?

Asthma attacks and symptoms usually get started by specific triggers (such as viruses, allergies, gases, and air particles). You should talk to your doctor about these triggers and find ways to avoid or get rid of them.

Did you know?

Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.

Did you know?

About 3.2 billion people, nearly half the world population, are at risk for malaria. In 2015, there are about 214 million malaria cases and an estimated 438,000 malaria deaths.

Did you know?

Everyone has one nostril that is larger than the other.

For a complete list of videos, visit our video library