After administering glimepiride, the nurse would assess the ...

[RODY.ELKHALIL]

After administering glimepiride, the nurse would assess the client for which of the following? Select all that apply.
 
  A) Lactic acidosis
  B) Edema
  C) Hypoglycemia
  D) Heartburn
  E) Nausea

Question 2

Which of the following produce their glucose-lowering effect by decreasing insulin resistance and increasing insulin sensitivity? Select all that apply.
 
  A) Rosiglitazone (Avandia)
  B) Metformin (Glucophage)
  C) Pioglitazone (Actos)
  D) Miglitol (Glyset)
  E) Acarbose (Precose)

[kkenney]

Answer to Question 1

Ans: C, D, E
Feedback:
Adverse reactions associated with sulfonylureas, like glimepiride (Amaryl), include hypoglycemia, anorexia, nausea, vomiting, epigastric discomfort, weight gain, heartburn, and various vague neurologic symptoms, such as numbness and weakness of the extremities.

Answer to Question 2

Ans: A, C
Feedback:
The thiazolidinediones, rosiglitazone (Avandia) and pioglitazone (Actos), produce their glucose-lowering effect by decreasing insulin resistance and increasing insulin sensitivity. The alpha-glucosidase inhibitors, acarbose (Precose) and miglitol (Glyset), produce their glucose-lowering effects by delaying the digestion and absorption of carbohydrates in the intestine. Metformin sensitizes the liver to circulating insulin levels and reduces hepatic glucose production.

[RODY.ELKHALIL]

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[kkenney]

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