The nurse is preparing to administer the antifungal medication ...

[jazziefee]

The nurse is preparing to administer the antifungal medication nystatin by mouth to an adult client. The nurse also has other PO medications to give to this client. How should the nurse administer the medications?
 
  1. Give the PO medications first.
  2. Give them at the same time.
  3. Give the nystatin first.
  4. Call the prescriber for clarification.

Question 2

The nurse is preparing to discharge a client with a prescription for zidovudine (Retrovir). Which drugs should the client avoid while taking this medication?(Select all that apply.)
 
  1. Aspirin
  2. Herbal supplements
  3. Penicillin (PCN)
  4. Acetaminophen (Tylenol)
  5. Oral multivitamin

[marict]

Answer to Question 1

1

Rationale 1: The client should wait at least 30 minutes after antifungal treatment to put anything else in the mouth, so the PO medication should be given before the nystatin.
Rationale 2: The client should wait at least 30 minutes after antifungal treatment to put anything else in the mouth, so the PO medication should be given before the nystatin.
Rationale 3:The PO medications should be given before the nystatin.
Rationale 4:The nurse should know that the PO medications should be given before the nystatin.

Global Rationale: The client should wait at least 30 minutes after antifungal treatment to put anything else in the mouth, so the PO medication should be given before the nystatin.

Answer to Question 2

1,2, 4

Rationale 1: Zidovudine interacts with many drugs. Acetaminophen and ganciclovir can worsen bone marrow depression. The following drugs can increase the risk of AZT toxicity: atovaquone, amphotericin B, aspirin, fluconazole, methadone, and valproic acid. Use with caution with herbal supplements, such as St.John's wort, which can cause a decrease in antiretroviral activity.
Rationale 2:Herbal supplements, such as St.John's wort, can cause a decrease in antiretroviral activity.
Rationale 3:Penicillin does not interact with zidovudine (AZT).
Rationale 4: Zidovudine interacts with many drugs. Acetaminophen and ganciclovir can worsen bone marrow depression. The following drugs can increase the risk of AZT toxicity: atovaquone, amphotericin B, aspirin, fluconazole, methadone, and valproic acid. Use with caution with herbal supplements, such as St.John's wort, which can cause a decrease in antiretroviral activity.
Rationale 5:The client can continue to take an oral multivitamin without an interaction with this medication.

Global Rationale: Zidovudine interacts with many drugs. Acetaminophen and ganciclovir can worsen bone marrow depression. The following drugs can increase the risk of AZT toxicity: atovaquone, amphotericin B, aspirin, fluconazole, methadone, and valproic acid. Use with caution with herbal supplements, such as St.John's wort, which can cause a decrease in antiretroviral activity. Multivitamins and penicillin do not cause a drug-to-drug interaction.

[jazziefee]

Thank you!

[marict]

Always glad to help...