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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
Illicit drug use costs the United States approximately $181 billion every year.
The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.
The most common treatment options for addiction include psychotherapy, support groups, and individual counseling.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.

