Which patients would be candidates for the use of dronabinol ...

[Caiter2013]

Which patients would be candidates for the use of dronabinol (Marinol) to treat nausea and vomiting? (Select all that apply.)
 
  a. A patient with a history of a psychiatric disorder
  b. A patient with acquired immunodeficiency syndrome (AIDS)induced anorexia
  c. A patient with chemotherapy-induced nausea and vomiting
  d. A patient with nausea who has used marijuana in the past
  e. A patient with postoperative nausea and vomiting

Question 2

A nurse is providing teaching to a nursing student about to care for a woman with irritable bowel syndrome with diarrhea (IBS-D) who is receiving alosetron (Lotronex).
 
  Which statement by the student indicates a need for further teaching?
  a. I should evaluate the patient's abdomen for distension and bowel sounds.
  b. Patients with diverticulitis and IBS-C may take this drug.
  c. There are no known serious drug interactions with alosetron.
  d. This drug is given only to women with severe IBS-D.

[Yixagurpuldink]

Answer to Question 1

ANS: B, C, D
Two cannabinoids have been approved for medical use in the United States for AIDS-induced anorexia and CINV. Because these drugs do not produce the same high that smoking marijuana does, their use is not contraindicated in patients who have used marijuana in the past. They do cause potentially unpleasant effects, such as temporal disintegration, dissociation, depersonalization, and dysphoria, so they are contraindicated in patients with psychiatric disorders. They are not approved for postoperative nausea and vomiting.

Answer to Question 2

ANS: B
Alosetron is approved for use in women only with diarrhea-predominant IBS; it is contraindicated in patients with diverticulitis. Constipation can be a severe adverse effect, so patients should be assessed for signs of constipation, such as abdominal distension and diminished bowel sounds. There are no known adverse interactions with other drugs. Alosetron is approved for use in women with IBS-D regardless of the severity of the disease.

[Caiter2013]

Excellent

[FergA]

TYSM