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Author Question: A patient with metastatic cancer has had several fractures secondary to bone metastases. The ... (Read 102 times)

casperchen82

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A patient with metastatic cancer has had several fractures secondary to bone metastases. The provider orders denosumab (Xgeva). What will the nurse teach this patient?
 
  a. Denosumab may delay healing of these fractures.
  b. Denosumab should be given subcutaneously every 12 months.
  c. Denosumab will improve hypocalcemia.
  d. Unlike bisphosphonates, denosumab does not increase osteonecrosis of the jaw (ONJ).

Question 2

A postmenopausal patient is at high risk for developing osteoporosis. The patient's prescriber orders raloxifene (Evista), and the nurse provides teaching about this drug. Which statement by the patient indicates understanding of the teaching?
 
  a. I may experience breast tenderness while taking this drug.
  b. I may experience fewer hot flashes while taking this drug.
  c. I should discontinue this drug several weeks before any surgery.
  d. I should walk as much as possible during long airline flights.



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adammoses97

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Answer to Question 1

ANS: A
Because denosumab suppresses bone turnover, fracture healing may be delayed. Denosumab is given every 6 months. Denosumab can exacerbate hypocalcemia. Denosumab can increase the incidence of ONJ.

Answer to Question 2

ANS: D
Like estrogen, raloxifene increases the risk of deep vein thrombosis. Patients taking this drug should be cautioned to take walks on long flights or whenever they must sit for long periods. The drug does not increase breast tenderness or decrease hot flashes. There is no need to discontinue this drug before surgery.





 

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