Author Question: A client's hormone replacement therapy for a health problem has been discontinued. The nurse should ... (Read 54 times)

jake · **on:** Jul 23, 2018

A client's hormone replacement therapy for a health problem has been discontinued. The nurse should instruct the client about which effects because the therapy has been stopped?

Standard Text: Select all that apply.
1. Body cells will need time to adjust to the new hormone level.
2. Target cells are desensitized and are less responsive to the effects of the hormone.
3. Body cells will create more receptors on the plasma membrane to capture hormone molecules.
4. Body cells will send signals that hormone action is needed.
5. Body cells will secrete more hormone.

Question 2

A client tells the nurse that because a hormone replacement medication was not working, the client started taking double the prescribed dose. How should the nurse respond to this client?

Standard Text: Select all that apply.
1. The health care provider will need to be notified, because hormonal balance falls within a narrow range.
2. It may take several days or longer to produce the desired effect.
3. That was not a very wise thing to do.
4. The wrong hormone replacement was prescribed.
5. The health care provider would have probably made the same decision.

lin77x · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 1,2
Rationale 1: When therapy is discontinued, the cells will need time to synthesize more protein receptors and adjust to the new hormone level.
Rationale 2: When a hormone is provided for long periods, the body recognizes an abundance of the hormone and cells will down-regulate the number of receptors for that hormone. This causes a desensitization of the target cells, and they are less responsive to the effects of the hormone.
Rationale 3: This does not occur when hormone replacement therapy is stopped.
Rationale 4: This does not occur when hormone replacement therapy is stopped.
Rationale 5: This does not occur when hormone replacement therapy is stopped.
Global Rationale: When a hormone is provided for long periods, the body recognizes an abundance of the hormone and cells will down-regulate the number of receptors for that hormone. This causes a desensitization of the target cells, and they are less responsive to the effects of the hormone. The cells will need time to synthesize more protein receptors and adjust to the new hormone level. The remaining responses do not occur when hormone therapy is discontinued.

Answer to Question 2

Correct Answer: 1,2
Rationale 1: Hormonal balance is kept within a narrow range. Too much of a hormone may cause profound physiological changes.
Rationale 2: Hormones from the endocrine system can affect all body cells and take as long as several days to produce optimum responses.
Rationale 3: Although the nurse may want to make this response, it is inappropriate. The nurse needs to explain why the dose of the hormone should not be increased without health care provider guidance.
Rationale 4: Hormone replacement may take several days or longer to produce the desired effects. The nurse has no way of knowing if the wrong hormone replacement was prescribed until the client experiences effects.
Rationale 5: Hormonal balance is kept within a narrow range. The nurse has no way of knowing what the health care provider would have done because the client was not yet experiencing the effects of the replacement.
Global Rationale: Hormonal balance is kept within a narrow range. Too much of a hormone may cause profound physiological changes. Hormones from the endocrine system can affect all body cells and take as long as several days to produce optimum responses. Although the nurse may want to admonish the patient, it is inappropriate. The nurse needs to explain why the dose of the hormone should not be increased without health care provider guidance. The nurse has no way of knowing if the wrong hormone replacement was prescribed until the client experiences effects. The nurse has no way of knowing what the health care provider would have done because the client was not yet experiencing the effects of the replacement.