Author Question: Which statement most accurately describes the cell kill hypothesis? 1. It is a model that ... (Read 26 times)

mikaylakyoung · **on:** Jul 23, 2018

Which statement most accurately describes the cell kill hypothesis?

1. It is a model that predicts the amount of normal cells that will be affected by antineoplastic drugs.
2. It is a model that predicts the ability of antineoplastic drugs to eliminate cancer cells.
3. It is a model that predicts how invasive a cancer has become.
4. It is a model that compares the appearance of potential cancer cells with that of normal parent cells.

Question 2

A client has been diagnosed with stage 4 pancreatic cancer. The family asks the nurse what staging is. The nurse explains that:

Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. Staging determines the location of the cancer.
2. The involvement of lymph nodes is assessed during staging.
3. Staging changes as the cancer progresses.
4. The lower the stage of cancer at diagnosis, the better the prognosis.
5. Staging examines cancerous cells under a microscope and compares them to normal cells.

Loise Hard · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 2
Rationale 1: This statement does not describe a particular model.
Rationale 2: This statement describes the cell kill hypothesis.
Rationale 3: This statement describes staging.
Rationale 4: This statement describes grading.
Global Rationale: The cell kill hypothesis is a theoretical model that predicts the ability of antineoplastic drugs to eliminate cancer cells. This hypothesis predicts that a drug will kill a certain percentage, rather than a constant number, of cancer cells. It does not predict the number of normal cells that will be affected. Staging gauges invasiveness. Grading compares cancerous cells to normal cells.

Answer to Question 2

Correct Answer: 1,2,4
Rationale 1: Staging does determine the location of the cancer.
Rationale 2: When solid tumors are staged, diagnostic testing also determines the involvement of the lymph nodes.
Rationale 3: Once a cancer is staged, the level does not change even if the cancer progresses.
Rationale 4: Clients with cancer at a lower stage have a better prognosis than those who are diagnosed at a higher stage.
Rationale 5: This describes cancer grading, not cancer staging.
Global Rationale: During the staging of solid tumors, diagnostic testing determines the size of the tumor, whether the tumor has invaded surrounding tissue, the involvement of lymph nodes, and the presence or absence of metastasis. Once a cancer is staged, the level does not change even if the cancer progresses. Clients with cancer at a lower stage have a better prognosis than those who are diagnosed at a higher stage. Comparison of cells occurs in grading, not staging.