Answer to Question 1
Correct Answer: 1
Rationale 1: The bacterial cell wall is rigid.
Rationale 2: The bacterial cell wall is nonpermeable.
Rationale 3: The bacterial cell wall is composed of carbohydrates and protein.
Rationale 4: The bacterial cell wall is multilayered.
Global Rationale: The cell wall is a structure that sets people apart from the bacterial world. Humans do not have them, but all bacteria do. The osmotic pressure is so high within a bacterial cell that the cell would rupture without the containment of this rigid structure. The cell wall also serves as a barrier to substances that try to enter the cell, including antibiotics. Simply, it protects the bacterial cell from a hostile environment.
Answer to Question 2
Correct Answer: 1,2
Rationale 1: Organisms that produce beta lactamase are resistant to many of the penicillins.
Rationale 2: Organisms that produce beta lactamase are resistant to many of the cephalosporins.
Rationale 3: Organisms that produce beta lactamase should be susceptible to macrolides.
Rationale 4: Organisms that produce beta lactamase should be susceptible to fluoroquinolones.
Rationale 5: Organisms that produce beta lactamase should be susceptible to sulfonamides.
Global Rationale: Organisms that produce beta lactamase are resistant to many of the penicillin and cephalosporin antibiotics.