Answer to Question 1
Correct Answer: 4
Rationale 1: The goal is prevention of rejection, and if treatment is held until signs of rejection are present, this is too late.
Rationale 2: Rejection is a significant possibility in all transplants.
Rationale 3: Immunosuppressants are designed to help prevent all types of rejection.
Rationale 4: Allografts always contain certain antigens that trigger the immune response and rejection, and immunosuppressants help prevent this response.
Global Rationale: Despite accurate tissue matching, allografts always contain certain antigens that have the potential to trigger the patient's immune defenses. This response, called transplant rejection, is often acute; antibodies sometimes destroy the transplanted tissue within 48 hours after a transplant. The goal is prevention of all types of rejection.
Answer to Question 2
Correct Answer: 1
Rationale 1: Cyclosporine and tacrolimus are calcineurin inhibitors.
Rationale 2: Cyclosporine and tacrolimus are not glucocorticoids.
Rationale 3: Cyclosporine and tacrolimus are not antimetabolites.
Rationale 4: Cyclosporine and tacrolimus are not antibodies.
Global Rationale: Two of the most important drugs in transplant medicine, cyclosporine (Sandimmune, Neoral) and tacrolimus (Prograf), are calcineurin inhibitors. These drugs revolutionized the pharmacotherapy of transplant rejection and have been the mainstay of transplant therapy since the 1980s. They are not members of the other classes.
The nurse needs to note the source of the patient health history
The nurse uses a noninvasive bladder ultrasound to measure the client’s bladder volume.
Erythroblastosis fetalis. (a) The condition occurs with an RH+ father and RH– mother. (b) First preg
nursing team
The five overlapping phases of the nursing process. Each phase depends on the accuracy of the other
Communication throughout the nursing process