A client who is prescribed losartan for hypertension is ...

[Pineappleeh]

A client who is prescribed losartan for hypertension is instructed to avoid using alcohol because of the risk of which adverse reaction?
 
  1. Alcohol intoxication
  2. Angioedema
  3. Lowered blood pressure
  4. Increased blood pressure

Question 2

The major difference in adverse effect profile between ACE inhibitors and ARBs is that ARBs do not cause which clinical manifestation?
 
  1. Headache
  2. Dizziness
  3. Angioedema
  4. Cough

[shaikhs]

Answer to Question 1

Correct Answer: 3
Rationale 1: Combining alcohol with losartan does not cause alcohol intoxication.
Rationale 2: Although there is a risk of angioedema with losartan therapy, combining the drug with alcohol does not increase the risk.
Rationale 3: Combining alcohol with losartan causes lowered blood pressure, which can lead to dizziness and faintness.
Rationale 4: Combining alcohol with losartan can lower blood pressure, not raise blood pressure.
Global Rationale: Combining alcohol with losartan causes lowered blood pressure, which can lead to dizziness and faintness. Combining alcohol with losartan does not cause alcohol intoxication. Although there is a risk of angioedema with losartan therapy, combining the drug with alcohol does not increase the risk. Losartan does not raise blood pressure.

Answer to Question 2

Correct Answer: 4
Rationale 1: ARBs can cause headaches, as can ACE inhibitors.
Rationale 2: ARBs can cause dizziness, as can ACE inhibitors.
Rationale 3: There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.
Rationale 4: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough.
Global Rationale: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough. ARBs and ACE inhibitors both can cause headaches and dizziness. There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.

[Pineappleeh]

TYSM

[jamesnevil303]

Excellent