Answer to Question 1
Correct Answer: 3
Rationale 1: Combining alcohol with losartan does not cause alcohol intoxication.
Rationale 2: Although there is a risk of angioedema with losartan therapy, combining the drug with alcohol does not increase the risk.
Rationale 3: Combining alcohol with losartan causes lowered blood pressure, which can lead to dizziness and faintness.
Rationale 4: Combining alcohol with losartan can lower blood pressure, not raise blood pressure.
Global Rationale: Combining alcohol with losartan causes lowered blood pressure, which can lead to dizziness and faintness. Combining alcohol with losartan does not cause alcohol intoxication. Although there is a risk of angioedema with losartan therapy, combining the drug with alcohol does not increase the risk. Losartan does not raise blood pressure.
Answer to Question 2
Correct Answer: 4
Rationale 1: ARBs can cause headaches, as can ACE inhibitors.
Rationale 2: ARBs can cause dizziness, as can ACE inhibitors.
Rationale 3: There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.
Rationale 4: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough.
Global Rationale: Since ARBs do not promote accumulation of bradykinin, they do not cause a cough. ARBs and ACE inhibitors both can cause headaches and dizziness. There is a risk of angioedema with ARB therapy, but it is less than that with ACE inhibitor therapy.