A nursing student asks the nurse educator why the actions of ...

[darbym82]

A nursing student asks the nurse educator why the actions of aldosterone lead to high blood pressure. Which of the educator's responses explain this phenomenon?
 
  Standard Text: Select all that apply.
  1. Aldosterone increases sodium reabsorption and the excretion of potassium and hydrogen by acting on the distal tubules.
  2. Aldosterone increases sodium reabsorption and the excretion of potassium and hydrogen by acting on the collecting tubules.
  3. Aldosterone increases sodium reabsorption and the excretion of potassium and hydrogen by acting on Bowman's capsule.
  4. Aldosterone increases sodium reabsorption and the excretion of potassium and hydrogen by acting on the glomerulus.
  5. Aldosterone increases sodium reabsorption and the excretion of potassium and hydrogen by acting on the Loop of Henle.

Question 2

Angiotensin-converting enzyme (ACE) inhibitor drugs function in the control of blood pressure by which mechanism of action?
 
  1. Blocking the effects of angiotensin II
  2. Blocking the conversion of angiotensin I to angiotensin II
  3. Blocking the conversion of angiotensin II to angiotensinogen
  4. Directly inhibiting renin

[Eunice618]

Answer to Question 1

Correct Answer: 1,2
Rationale 1: Aldosterone acts on the distal tubules of the nephron to increase Na+ reabsorption and K+ and H+ excretion. The enhanced sodium reabsorption from both direct and indirect actions of angiotensin II causes the body to retain water, thus increasing blood volume and raising blood pressure.
Rationale 2: Aldosterone acts on the collecting tubules of the nephron to increase Na+ reabsorption and K+ and H+ excretion. The enhanced sodium reabsorption from both direct and indirect actions of angiotensin II causes the body to retain water, thus increasing blood volume and raising blood pressure.
Rationale 3: Aldosterone does not increase blood pressure by acting on Bowman's capsule.
Rationale 4: Aldosterone does not increase blood pressure by acting on the glomerulus.
Rationale 5: Aldosterone does not increase blood pressure by acting on the Loop of Henle.
Global Rationale: Aldosterone acts on the distal tubules and the collecting tubules of the nephron to increase Na+ reabsorption and K+ and H+ excretion. The enhanced sodium reabsorption from both direct and indirect actions of angiotensin II causes the body to retain water, thus increasing blood volume and raising blood pressure. Aldosterone does not increase blood pressure by acting on Bowman's capsule, the glomerulus, or on the Loop of Henle.

Answer to Question 2

Correct Answer: 2
Rationale 1: ACE inhibitors do not block the effects of angiotensin II, but of angiotensin I.
Rationale 2: ACE inhibitors prevent conversion of angiotensin I to angiotensin II.
Rationale 3: Angiotensin II does not convert to angiotensinogen.
Rationale 4: ACE inhibitors do not block renin.
Global Rationale: ACE inhibitors prevent conversion of angiotensin I to angiotensin II which controls blood pressure. ACE inhibitors do not block the effects of angiotensin II. Angiotensin II does not convert to angiotensinogen. ACE inhibitors do not block renin.

[darbym82]

Excellent

[dantucker]

TYSM