Answer to Question 1
Correct Answer: 3
Rationale 1: Cholinergic synapses utilize acetylcholine, and play a role in Parkinson and Alzheimer diseases.
Rationale 2: Adrenergic synapses utilize norepinephrine to heighten alertness. Adrenergic neurons likely play a role in mood disorders.
Rationale 3: Cocaine and amphetamines produce their stimulatory actions by affecting dopamine receptors.
Rationale 4: Glutamate is always excitatory and can be neurotoxic at high levels.
Global Rationale: Cocaine and amphetamines produce their stimulatory actions by affecting dopamine receptors. Cholinergic synapses utilize acetylcholine, and play a role in Parkinson and Alzheimer diseases. Adrenergic synapses utilize norepinephrine to heighten alertness. Adrenergic neurons likely play a role in mood disorders. Glutamate is always excitatory and can be neurotoxic at high levels.
Answer to Question 2
Correct Answer: 2
Rationale 1: Glutamate is an excitatory neurotransmitter associated with memory.
Rationale 2: Low serotonin levels in the CNS are associated with anxiety and impulsive behavior, including suicidal ideation. Serotonergic receptors play an important role in the mechanism of action of antidepressant drugs.
Rationale 3: Dopamine is associated with Parkinson disease, psychoses, motivation, and pleasure.
Rationale 4: Acetylcholine is associated with myasthenia gravis and Alzheimer disease.
Global Rationale: Low serotonin levels in the CNS are associated with anxiety and impulsive behavior, including suicidal ideation. Serotonergic receptors play an important role in the mechanism of action of antidepressant drugs. Glutamate is an excitatory neurotransmitter associated with memory. Dopamine is associated with Parkinson disease, psychoses, motivation, and pleasure. Acetylcholine is associated with myasthenia gravis and Alzheimer disease.
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