A client on long-term therapy with itraconazole (Sporanox) for ...

[jman1234]

A client on long-term therapy with itraconazole (Sporanox) for treatment of a nail fungus is admitted to the hospital with right upper quadrant pain, nausea, and abdominal pain.
 
  Which laboratory results found in the medical record would support the diagnosis of hepatotoxicity?
  1. Elevated liver function tests
  2. Elevated creatinine levels
  3. Decreased blood sugar
  4. Decreased prothrombin time

Question 2

Which clinical manifestation would the nurse identify as an allergic reaction?
 
  1. Urticaria
  2. Photosensitivity
  3. Abdominal cramping
  4. Complaints of diarrhea

[debra928]

Answer to Question 1

Correct Answer: 1
Rationale 1: Elevated liver function tests, which include the enzymes ALT and AST, are indicative of liver inflammation and/or impaired function of the liver.
Rationale 2: Elevated creatinine levels are indicative of impaired renal function.
Rationale 3: A decreased blood sugar indicates hypoglycemia, which has many causes, but is not related to hepatotoxicity.
Rationale 4: Impaired liver function would cause an increased or prolonged prothrombin time.
Global Rationale: Elevated liver function tests, which include the enzymes ALT and AST, are indicative of liver inflammation and/or impaired function of the liver. Elevated creatinine levels are indicative of impaired renal function. A decreased blood sugar indicates hypoglycemia, which has many causes, but is not related to hepatotoxicity. Impaired liver function would cause an increased or prolonged prothrombin time.

Answer to Question 2

Correct Answer: 1
Rationale 1: Urticaria, or hives, is indicative of an allergic response to a medication.
Rationale 2: Photosensitivity is a predictable side effect of some medications.
Rationale 3: Abdominal cramping could be a side effect or adverse effect of medications.
Rationale 4: Diarrhea is a common side effect of many medications.
Global Rationale: Urticaria, or hives, is indicative of an allergic response to a medication. Photosensitivity is a predictable side effect of some medications. Abdominal cramping could be a side effect or adverse effect of medications. Diarrhea is a common side effect of many medications.

[jman1234]

TY

[debra928]

You're welcome