This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: The nurse is caring for a patient who recently receive a renal transplant. The patient is taking ... (Read 84 times)

formula1

  • Hero Member
  • *****
  • Posts: 666
on: Jul 23, 2018
The nurse is caring for a patient who recently receive a renal transplant. The patient is taking sirolimus (Rapamune) to prevent transplant rejection. What other medications would the nurse expect the patient to be taking?
 
  a. Rifampin and ketoconazole
  b. Carbamazepine and phenobarbital
  c. Cyclosporine and glucocorticoids
  d. Amphotericin B and erythromycin

Question 2

Which drug, when given concurrently with cyclosporine (Sandimmune), can inhibit hepatic microsomal enzymes and lead to toxic levels of cyclosporine?
 
  a. Phenytoin (Dilantin)
  b. Rifampin (Rifadin)
  c. Erythromycin
  d. Trimethoprim-sulfamethoxazole (Bactrim)


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

trampas

  • Sr. Member
  • ****
  • Posts: 320
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: C
Sirolimus should be used in conjunction with cyclosporine and glucocorticoids to reduce the risk of transplant rejection.
Rifampin can reduce and ketoconazole can increase therapeutic levels of sirolimus and cyclosporine, therefore they are not indicated for transplant patients.
Carbamazepine and phenobarbital are not indicated, because they can reduce the therapeutic levels of sirolimus and cyclosporine.
Amphotericin B and erythromycin are not indicated, because they can increase the therapeutic levels of sirolimus and cyclosporine.

Answer to Question 2

ANS: C
Erythromycin can elevate microsomal enzymes, leading to increased levels of cyclosporine.
Phenytoin, rifampin, and trimethoprim-sulfamethoxazole reduce the levels of cyclosporine in the body.


formula1

  • Member
  • Posts: 666
Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it

miss.ashley

  • Member
  • Posts: 371
Reply 3 on: Yesterday
Wow, this really help

« previous next »
 

Did you know?

A strange skin disease referred to as Morgellons has occurred in the southern United States and in California. Symptoms include slowly healing sores, joint pain, persistent fatigue, and a sensation of things crawling through the skin. Another symptom is strange-looking, threadlike extrusions coming out of the skin.

Did you know?

In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.

Did you know?

The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.

Did you know?

Elderly adults are living longer, and causes of death are shifting. At the same time, autopsy rates are at or near their lowest in history.

Did you know?

Only 12 hours after an egg cell is fertilized by a sperm cell, the egg cell starts to divide. As it continues to divide, it moves along the fallopian tube toward the uterus at about 1 inch per day.

Example of problem focused patient Example of problem focused patient
Position of patient following seizure Position of patient following seizure
Building competency in patient centered care Building competency in patient centered care
Severe periodontitis in a patient with uncontrolled diabetes. Severe periodontitis in a patient with uncontrolled diabetes.
Jia's Fashions recently paid a $2 annual dividend. The company is projecting that its ... Jia's Fashions recently paid a $2 annual dividend. The company is projecting that its ...
Illustration of the anatomy of a normal subject (A) and a patient with sleep apnea (B) Illustration of the anatomy of a normal subject (A) and a patient with sleep apnea (B)
Video: Aneurysm

For a complete list of videos, visit our video library