This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: The nurse is caring for a patient who recently receive a renal transplant. The patient is taking ... (Read 46 times)

formula1

  • Hero Member
  • *****
  • Posts: 666
on: Jul 23, 2018
The nurse is caring for a patient who recently receive a renal transplant. The patient is taking sirolimus (Rapamune) to prevent transplant rejection. What other medications would the nurse expect the patient to be taking?
 
  a. Rifampin and ketoconazole
  b. Carbamazepine and phenobarbital
  c. Cyclosporine and glucocorticoids
  d. Amphotericin B and erythromycin

Question 2

Which drug, when given concurrently with cyclosporine (Sandimmune), can inhibit hepatic microsomal enzymes and lead to toxic levels of cyclosporine?
 
  a. Phenytoin (Dilantin)
  b. Rifampin (Rifadin)
  c. Erythromycin
  d. Trimethoprim-sulfamethoxazole (Bactrim)


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

trampas

  • Sr. Member
  • ****
  • Posts: 320
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: C
Sirolimus should be used in conjunction with cyclosporine and glucocorticoids to reduce the risk of transplant rejection.
Rifampin can reduce and ketoconazole can increase therapeutic levels of sirolimus and cyclosporine, therefore they are not indicated for transplant patients.
Carbamazepine and phenobarbital are not indicated, because they can reduce the therapeutic levels of sirolimus and cyclosporine.
Amphotericin B and erythromycin are not indicated, because they can increase the therapeutic levels of sirolimus and cyclosporine.

Answer to Question 2

ANS: C
Erythromycin can elevate microsomal enzymes, leading to increased levels of cyclosporine.
Phenytoin, rifampin, and trimethoprim-sulfamethoxazole reduce the levels of cyclosporine in the body.


formula1

  • Member
  • Posts: 666
Reply 2 on: Jul 23, 2018
Gracias!

blakcmamba

  • Member
  • Posts: 335
Reply 3 on: Yesterday
Wow, this really help

« previous next »
 

Did you know?

Always store hazardous household chemicals in their original containers out of reach of children. These include bleach, paint, strippers and products containing turpentine, garden chemicals, oven cleaners, fondue fuels, nail polish, and nail polish remover.

Did you know?

Approximately 500,000 babies are born each year in the United States to teenage mothers.

Did you know?

You should not take more than 1,000 mg of vitamin E per day. Doses above this amount increase the risk of bleeding problems that can lead to a stroke.

Did you know?

When taking monoamine oxidase inhibitors, people should avoid a variety of foods, which include alcoholic beverages, bean curd, broad (fava) bean pods, cheese, fish, ginseng, protein extracts, meat, sauerkraut, shrimp paste, soups, and yeast.

Did you know?

Individuals are never “cured” of addictions. Instead, they learn how to manage their disease to lead healthy, balanced lives.

Patient Teaching Methods Cont. Patient Teaching Methods Cont.
An ultrasound being performed on a patient. An ultrasound being performed on a patient.
Taking a blood pressure is one of the procedures the medical assistant extern may perform under the ... Taking a blood pressure is one of the procedures the medical assistant extern may perform under the ...
Examples of endocrine disorders. (C) A patient with congenital hypothyroidism. Examples of endocrine disorders. (C) A patient with congenital hypothyroidism.
Manifestations of chronic renal failure. Manifestations of chronic renal failure.
Patient with DiGeorge syndrome. Note low set ears and wide set downward slanting eyes; often these ... Patient with DiGeorge syndrome. Note low set ears and wide set downward slanting eyes; often these ...
Video: Enzyme-Catalyzed Reactions

For a complete list of videos, visit our video library