Answer to Question 1
ANS: B
Epoetin alfa has been associated with an increase in cardiovascular events. The risk is greatest when the hemoglobin level exceeds 12 gm/dL.
No relationship exists between the hematocrit, basophil, or neutrophil levels and cardiac events in patients taking epoetin alfa.
Answer to Question 2
ANS: A
Filgrastim causes bone pain in about 25 of patients. The pain is dose related and usually mild to moderate.
Fatigue, bleeding, and headache are not side effects of filgrastim.