Answer to Question 1
ANS: B
Cardiotoxicity is a known adverse effect of this drug and is manifested in shortness of breath, edema, and palpitations.
Answer to Question 2
ANS: C
Hemorrhagic cystitis is a common adverse effect of high-dose cyclophosphamide and can be mitigated by increasing fluid intake. Allopurinol is given to treat gout, which is characterized by uric acid crystalluria. Darkening of the fingernails and skin is a common adverse effect of cyclophosphamide but is unrelated to hemorrhagic cystitis.