This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient with HIV infection has been receiving antiretroviral therapy for 2 months. At the ... (Read 64 times)

123654777

  • Hero Member
  • *****
  • Posts: 585
on: Jul 23, 2018
A patient with HIV infection has been receiving antiretroviral therapy for 2 months. At the initiation of treatment, the patient had a viral load (VL) of 60 copies/mL and a CD4 count of 450 cells/mm3.
 
  Today's lab results reveal a VL of 20 copies/mL and a CD4 cell count of 800 cells/mm3. How will the nurse interpret the patient's results?
  a. A drug-resistant strain is likely.
  b. The patient is progressing as expected.
  c. The patient's treatment goals have been met.
  d. Treatment failure has occurred.

Question 2

A patient who is HIV-positive begins therapy with the fixed-dose combination nucleoside reverse transcriptase inhibitor (NRTI) Combivir (lamivudine/zidovudine) twice daily.
 
  The patient is in the clinic for follow-up 1 week after initiation of therapy and reports having nausea. The patient's creatinine clearance is 40 mL/minute. Based on these findings, the nurse will perform which action?
  a. Instruct the patient to take the medication 60 minutes prior to meals.
  b. Notify the provider to discuss single-dose NRTI products.
  c. Request an order for once-daily dosing of this medication.
  d. Suggest that the patient increase fluid intake.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Natalie4ever

  • Sr. Member
  • ****
  • Posts: 335
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
The treatment goal would be a VL of < 20 copies/mL and a CD4 cell count between 800 and 1200 cells/mm3. This goal should be achieved in 16 to 24 weeks. Since this patient has shown improvement, progress has been made, and treatment should continue. A drug-resistant strain is not likely to respond to therapy. Treatment failure is not evident.

Answer to Question 2

ANS: B
Patients should have dosage adjustments of NRTIs if creatinine clearance is less than 50 mL/min. The patient will need single-dose medications so that adjustments can be made. Taking the medication prior to meals improves absorption of didanosine but does not alter the side effect of nausea for Combivir, which should subside in the next week or so. This combination product is not given once daily. Increasing fluid intake will not affect this patient's symptoms.


123654777

  • Hero Member
  • *****
  • Posts: 585
Reply #2 on: Jul 23, 2018
Thanks


Natalie4ever

  • Sr. Member
  • ****
  • Posts: 335
Reply #3 on: Jul 23, 2018
Welcome :)


« previous next »
 

Did you know?

Fatal fungal infections may be able to resist newer antifungal drugs. Globally, fungal infections are often fatal due to the lack of access to multiple antifungals, which may be required to be utilized in combination. Single antifungals may not be enough to stop a fungal infection from causing the death of a patient.

Did you know?

About 100 new prescription or over-the-counter drugs come into the U.S. market every year.

Did you know?

More than 50% of American adults have oral herpes, which is commonly known as "cold sores" or "fever blisters." The herpes virus can be active on the skin surface without showing any signs or causing any symptoms.

Did you know?

Every 10 seconds, a person in the United States goes to the emergency room complaining of head pain. About 1.2 million visits are for acute migraine attacks.

Did you know?

GI conditions that will keep you out of the U.S. armed services include ulcers, varices, fistulas, esophagitis, gastritis, congenital abnormalities, inflammatory bowel disease, enteritis, colitis, proctitis, duodenal diverticula, malabsorption syndromes, hepatitis, cirrhosis, cysts, abscesses, pancreatitis, polyps, certain hemorrhoids, splenomegaly, hernias, recent abdominal surgery, GI bypass or stomach stapling, and artificial GI openings.

The tone of the nurse-patient introduction sets the stage for the patient interview and patient care The tone of the nurse-patient introduction sets the stage for the patient interview and patient care
Inflammation. Inflammation is characterized by the presence of swelling, redness, heat, and pain. Sw Inflammation. Inflammation is characterized by the presence of swelling, redness, heat, and pain. Sw
Patient teaching: male genetalia assessment Patient teaching: male genetalia assessment
Sample new patient registration form. Sample new patient registration form.
A patient undergoing hemodialysis. A patient undergoing hemodialysis.
Radiation therapy. Radiation therapy.
Video: New DNA Strand Replication

For a complete list of videos, visit our video library