Answer to Question 1
ANS: C
In adolescence, hormonal changes and growth spurts may necessitate changes in medication dosages; many children with chronic illness require dosage adjustments in the early teen years.
Answer to Question 2
ANS: B
Neonates and young infants tend to have less body fat than older children, meaning that they need less of fat-soluble medications since these medications won't be bound in fat tissue. Higher doses would lead to drug toxicity. Body fat does not affect the frequency of dosing.