This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient has been taking warfarin (Coumadin), which is highly protein-bound. The patient will begin ... (Read 47 times)

mynx

  • Hero Member
  • *****
  • Posts: 555
on: Jul 23, 2018
A patient has been taking warfarin (Coumadin), which is highly protein-bound. The patient will begin taking gemfibrozil, which is also highly protein-bound. The nurse will observe the patient closely for
 
  a. decreased effects of warfarin.
  b. increased effects of warfarin.
  c. decreased effects of gemfibrozil.
  d. decreased effects of both drugs.

Question 2

A patient is taking phenytoin to prevent seizures. The nurse knows that phenytoin is highly protein-bound and has sedative side effects. The nurse reviews the patient's chart and notes a low serum albumin.
 
  The nurse will notify the provider and observe the patient for which effects?
  a. Decreased sedative effects
  b. Increased sedative effects
  c. Increased seizures
  d. No change in effects


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

gabrielle_lawrence

  • Sr. Member
  • ****
  • Posts: 353
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
The addition of a highly protein-bound drug will compete with warfarin for protein- binding sites, releasing more free warfarin into the system, increasing drug effects and increasing the chance of toxicity.

Answer to Question 2

ANS: B
Phenytoin is protein-bound. When patients have a low serum albumin, there are fewer protein-binding sites, leaving more free drug in the system. The nurse should expect an increase in sedative side effects.


mynx

  • Member
  • Posts: 555
Reply 2 on: Jul 23, 2018
Gracias!

DylanD1323

  • Member
  • Posts: 314
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.

Did you know?

Medication errors are more common among seriously ill patients than with those with minor conditions.

Did you know?

Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.

Did you know?

Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.

Did you know?

Hip fractures are the most serious consequences of osteoporosis. The incidence of hip fractures increases with each decade among patients in their 60s to patients in their 90s for both women and men of all populations. Men and women older than 80 years of age show the highest incidence of hip fractures.

Protein–protein interaction Protein–protein interaction
An overview of protein synthesis. An overview of protein synthesis.
Testing Visual Fields by Confrontation: The nurse and patient should be approximately at an eye to e Testing Visual Fields by Confrontation: The nurse and patient should be approximately at an eye to e
Human hnRNP A1 protein can cycle in and out of the cytoplasm, but human hnRNP C Human hnRNP A1 protein can cycle in and out of the cytoplasm, but human hnRNP C
A medical assistant listening to the patient and physician discuss the patient's care. A medical assistant listening to the patient and physician discuss the patient's care.
Comparison of DNA polymerase structures with primer and template bound Comparison of DNA polymerase structures with primer and template bound
Video: Photosynthesis overview Animation

For a complete list of videos, visit our video library