A patient who is taking clopidogrel Plavix calls the nurse to ...

[luvbio]

A patient who is taking clopidogrel Plavix calls the nurse to report black, tarry stools and coffee-ground emesis. The nurse will tell the patient to:
 
  a. ask the provider about using aspirin in-stead of clopidogrel.
  b. consume a diet high in vitamin K.
  c. continue taking the clopidogrel until talk-ing to the provider.
  d. stop taking the clopidogrel immediately.

Question 2

A nurse administers warfarin (Coumadin) to a patient who is concurrently taking drug X, which also is highly protein bound. The nurse would anticipate that drug X will act at the receptor site as a
 
  a. competitive agonist.
  b. sympathomimetic.
  c. competitive antagonist.
  d. parasympathomimetic .

[elizabethrperez]

Answer to Question 1

C
Patients who experience bleeding should be warned not to stop taking the clopidogrel until the prescriber says they should, since abrupt withdrawal may precipitate a thrombotic event. Taking aspirin with an active GI bleed is contraindicated. Warfarin is a vitamin K inhibitor; consuming extra vitamin K will not reverse the effects of clopidogrel.

Answer to Question 2

C
Because both drugs are highly protein bound, they will be competing for the same receptor site; they therefore are competitive antagonists, which increases the risk of toxicity.
Competitive agonists are drugs that compete for the same receptor site but do not potentiate the effects of the drugs.
A sympathomimetic effect mimics the effects of the sympathetic nervous system.
A parasympathomimetic effect mimics the effects of the PNS.

DIF: Cognitive Level: Analysis REF: p. 37
TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

[luvbio]

Both answers were spot on, thank you once again

[elizabethrperez]

Great! Please up vote