A patient with type 2 diabetes mellitus takes glipizide. The ...

[Collmarie]

A patient with type 2 diabetes mellitus takes glipizide. The patient develops a urinary tract infection, and the prescriber orders TMP/SMZ. What will the nurse tell the patient?
 
  a. Patients with diabetes have an increased risk of an allergic reaction.
  b. Patients taking TMP/SMZ may need in-creased doses of glipizide.
  c. The patient should check the blood glu-cose level more often while taking TMP/SMZ.
  d. The patient should stop taking the glipi-zide while taking the TMP/SMZ.

Question 2

A patient who takes nitroglycerine to treat stable angina reports having erectile dysfunction and states that he plans to ask his primary provider for a prescription for tadalafil Cialis. What will the nurse tell this patient?
 
  a. You may take these two drugs together safely as long as you take them as di-rected.
  b. You should not take tadalafil and nitrog-lycerine within 30 to 60 minutes of each other.
  c. You should discuss another anti-angina medication with your provider.
  d. You should avoid sexual activity since this increases oxygen demands on the heart.

[Ashley I]

Answer to Question 1

C
Sulfonamides can intensify the effects of some drugs, including glipizide, which is a sulfonylu-rea-type hypoglycemic medication. These drugs may require a reduction in dose to prevent tox-icity. Patients should monitor their blood glucose more closely. There is no increase in allergic reactions to TMP/SMZ in patients who are diabetic. Patients taking TMP/SMZ may need re-duced doses of glipizide but should not stop taking the drug.

Answer to Question 2

C
Use of nitroglycerine with any phosphodiesterase type 5 inhibitor, such as sildenafil or tadalafil is absolutely contraindicated. The patient should be advised to discuss another antianginal agent with the provider. Patients should be taught to increase all activity to maintain as normal a life-style as possible.

[Collmarie]

Thanks for the timely response, appreciate it

[debra928]

TYSM