The nurse promotes optimal drug effectiveness by doing what? ...

[ashley]

The nurse promotes optimal drug effectiveness by doing what? (Select all that apply.)
 
  A) Incorporate basic history and physical assessment factors into the plan of care.
  B) Evaluate the effectiveness of drugs after they have been administered.
  C) Modify the drug regimen to modify adverse or intolerable effects.
  D) Minimize the number of medications administered to patients.
  E) Examine factors known to influence specific drugs if they are to be effective.

Question 2

Pyrimethamine (Daraprim) has been ordered for the patient as prophylactic treatment of malaria. The nurse recognizes the action of this drug prevents relapse of the disease by acting on what?
 
  A) Changing the metabolic pathways for reproduction
  B) Disrupting the mitochondria of the plasmodium
  C) Blocking the use of folic acid
  D) Increasing the acidity of plasmodial food vacuoles

[epscape]

Answer to Question 1

A, B, C, E
Feedback:
Incorporate basic history and physical assessment factors into any plan of care so that obvious problems can be identified and handled promptly. If a drug simply does not do what it is expected to do, further examine the factors that are known to influence drug effects. Frequently, the drug regimen can be modified to deal with that influence. Minimizing the number of medications administered is usually not an option because each drug is ordered for a reason of necessity for the patient.

Answer to Question 2

C
Feedback:
Pyrimethamine is used in combination with agents that act more rapidly to suppress malaria; it acts by blockings the use of folic acid in protein synthesis by the plasmodium, eventually leading to inability to reproduce and cell death. Chloroquine changes the metabolic pathways for reproduction of the plasmodium and is toxic to parasites that absorb it. Primaquine disrupts the mitochondria of the plasmodium. Mefloquine increases the acidity of plasmodial food vacuoles causing cell rupture and death.

[ashley]

Thank you!

[epscape]

Always glad to help...