When involved in phase III drug evaluation studies, what ...

[nautica902]

When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
 
  A) Working with animals who are given experimental drugs
  B) Choosing appropriate patients to be involved in the drug study
  C) Monitoring and observing patients closely for adverse effects
  D) Conducting research to determine effectiveness of the drug

Question 2

A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
 
  Under what category would morphine be classified? A) Schedule I
  B) Schedule II
  C) Schedule III
  D) Schedule IV

[kristenb95]

Answer to Question 1

C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to record any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect and analyze the information to be shared with the Food and Drug Administration (FDA) but would not conduct research independently because nurses do not prescribe medications. Use of animals in drug testing is done in the preclinical trials. Select patients who are involved in phase II studies to participate in studies where the participants have the disease the drug is intended to treat. These patients are monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.

Answer to Question 2

B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse potential and limited dependence liability.

[nautica902]

Excellent

[JaynaD87]

TYSM