Author Question: A patient is administered imipenemcilastatin for the treatment of an E. coli infection. The nurse ... (Read 33 times)

ishan · **on:** Jul 23, 2018

A patient is administered imipenemcilastatin for the treatment of an E. coli infection. The nurse should be aware that cilastatin is combined with the imipenem for what purpose?

A) To eliminate adverse effects of imipenem administration
B) To inhibit the destruction of imipenem
C) To potentiate the therapeutic effects of imipenem
D) To allow imipenem to cross the bloodbrain barrier

Question 2

A patient with iron deficiency anemia has begun taking daily supplements of oral ferrous sulfate. The nurse who is planning this patient's care should add what nursing diagnosis to the nursing care plan?

A) Risk for excess fluid volume related to use of iron supplements
B) Risk for unstable blood glucose related to use of iron supplements
C) Risk for constipation related to use of iron supplements
D) Risk for peripheral neurovascular dysfunction related to use of iron supplements

lindahyatt42 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

B
Feedback:
Cilastatin inhibits the destruction of imipenem, increasing the urinary concentration of imipenem and reducing its potential renal toxicity. It does not allow the drug to cross the bloodbrain barrier, and cilastatin does not eliminate all adverse effects.

Answer to Question 2

C
Feedback:
Constipation is a common adverse effect of iron supplements. Neurovascular dysfunction, fluid volume excess, and unstable blood glucose are unlikely to result from iron supplements.