A nurse is reviewing a new patient's admission blood work, which ...

[jerry coleman]

A nurse is reviewing a new patient's admission blood work, which indicates that the patient's glomerular filtration rate is 51 mL/min/1.73 m2 (low). What implication does this have for the patient's subsequent pharmacotherapy?
 
  A) The patient may need lower-than-normal doses of some medications.
  B) The patient may require a fluid challenge prior to medication administration.
  C) The patient may need IV administration of a hypotonic solution to aid medication excretion.
  D) The patient may need to receive medications by topical and subcutaneous routes rather than parenteral.

Question 2

A neonate is diagnosed with patent ductus arteriosus. What nonsteroidal anti-inflammatory agent is administered intravenously for treatment of this congenital heart defect?
 
  A) Sulindac (Clinoril)
  B) Etodolac
  C) Nabumetone ( Relafen)
  D) Indomethacin (Indocin)

[lorealeza77]

Answer to Question 1

A
Feedback:
With a decreased GFR, it is necessary to reduce the dosage of the medication. IV fluid administration and alternative routes do not adequately compensate for this change in pharmacokinetics.

Answer to Question 2

D