What is the advantage of combination therapy using cell ...

[EAugust]

What is the advantage of combination therapy using cell cycle-specific and cell cycle-nonspecific agents?
 
  a. Decreased expense and time needed for administration
  b. Decreased toxicity to patients and the nurses who administer the drug
  c. Increased cell death in various cycles and decreased toxicity
  d. Increased rate of treatment success

Question 2

Why is a patient with prostate cancer prescribed an estrogen?
 
  a. To achieve hormonal balance
  b. To decrease the rate of production for malignant cells
  c. To soften prostatic tissue
  d. To suppress prostate gland function

[Ptupou85]

Answer to Question 1

ANS: D
Combination therapy is far superior to the use of single agent therapy. The use of a cell cycle-specific and cell cycle-nonspecific agents together facilitates cell death during different phases of the cell cycle. Combination therapy is not more economical or faster. Combination therapy is not less toxic because it exposes patients and nurses to additional medications. The use of combination drug therapy allows for cell death during different phases of the cell cycle, but the agents often have toxic effects on different organs at different time intervals after administration.

Answer to Question 2

ANS: B
Estrogen therapy is used during the treatment of prostate cancer to decrease the rate of production of malignant cells. The use of female hormones decreases the amount of male hormones available for use by the cancer cells. Estrogen is not given for hormonal balance, does not soften prostatic tissue, and does not suppress prostate gland function.

[EAugust]

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[Ptupou85]

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