This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 ... (Read 99 times)

bobypop

  • Hero Member
  • *****
  • Posts: 539
on: Jul 24, 2018
The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago. The patient has a history of coronary artery disease and takes an antihypertensive and aspirin.
 
  Which information would support the need for a reduction in medication dosage by the health care provider?
  a. Constipation
  b. Brownish orange urine
  c. Drowsiness
  d. Dizziness

Question 2

What is the pharmacologic action of entacapone, a potent catechol O methyl transferase (COMT) inhibitor?
 
  a. Slows the deterioration of dopaminergic nerve cells
  b. Inhibits the relative excess of dopaminergic activity
  c. Reduces the destruction of dopamine in peripheral tissues
  d. Enhances the cholinergic symptoms of Parkinson's disease


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

katara

  • Sr. Member
  • ****
  • Posts: 305
Reply #1 on: Jul 24, 2018
Answer to Question 1

ANS: D
Dizziness is a symptom of orthostatic hypotension; dosages may need to be altered. Constipation is an expected adverse effect of this medication. Brownish orange urine is an expected adverse effect of this medication. Drowsiness is an expected adverse effect that occurs when therapy is initiated.

Answer to Question 2

ANS: C
Entacapone, a COMT inhibitor, reduces dopamine destruction in peripheral tissues. This significantly increases the amount of dopamine available to reach the brain. Entacapone, when used with carbidopa levodopa therapy, results in more constant dopaminergic stimulation. Entacapone is not effective when used alone. Entacapone does not affect the nerve cells but blocks enzymes that break down levodopa. Parkinson's disease is characterized by a relative deficit of dopaminergic activity. Entacapone does not affect cholinergic symptoms of Parkinson's disease.


bobypop

  • Member
  • Posts: 539
Reply 2 on: Jul 24, 2018
Great answer, keep it coming :)

JaynaD87

  • Member
  • Posts: 368
Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

« previous next »
 

Did you know?

An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.

Did you know?

According to the American College of Allergy, Asthma & Immunology, more than 50 million Americans have some kind of food allergy. Food allergies affect between 4 and 6% of children, and 4% of adults, according to the CDC. The most common food allergies include shellfish, peanuts, walnuts, fish, eggs, milk, and soy.

Did you know?

Immunoglobulin injections may give short-term protection against, or reduce severity of certain diseases. They help people who have an inherited problem making their own antibodies, or those who are having certain types of cancer treatments.

Did you know?

Colchicine is a highly poisonous alkaloid originally extracted from a type of saffron plant that is used mainly to treat gout.

Did you know?

Pregnant women usually experience a heightened sense of smell beginning late in the first trimester. Some experts call this the body's way of protecting a pregnant woman from foods that are unsafe for the fetus.

Example of problem focused patient Example of problem focused patient
Bovine Spongiform Encephalopathy and Creutzfeldt-Jakob Disease Bovine Spongiform Encephalopathy and Creutzfeldt-Jakob Disease
Many ideologies stem from older theories. The ideas of the philosophers are simplified. Ideologies Many ideologies stem from older theories. The ideas of the philosophers are simplified. Ideologies
Empathy draws a more positive response from the patient because it is based on the willingness of th Empathy draws a more positive response from the patient because it is based on the willingness of th
A pharmacist can explain to a patient why medication may look different and ensure the correct ... A pharmacist can explain to a patient why medication may look different and ensure the correct ...
Men who are at risk for heart disease and report work-related stressors are at greater risk of death ... Men who are at risk for heart disease and report work-related stressors are at greater risk of death ...
Video: Plant Defense Mechanisms from Pathogens

For a complete list of videos, visit our video library