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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.