Author Question: Samantha is taking lamotrigine (Lamictal) for her seizures and requests a prescription for combined ... (Read 83 times)

maychende · **on:** Jul 24, 2018

Samantha is taking lamotrigine (Lamictal) for her seizures and requests a prescription for combined oral contraceptives (COCs), which interact with lamotrigine and may cause:

1. Contraceptive failure
2. Excessive weight gain
3. Reduced lamotrigine levels, requiring doubling the dose of lamotrigine
4. Induction of estrogen metabolism, requiring higher estrogen content OCs be prescribed

Question 2

Zainab is taking lamotrigine (Lamictal) and presents to the clinic with fever and lymphadenopathy. Initial evaluation and treatment includes:

1. Reassuring her she has a viral infection and to call if she isn't better in 4 or 5 days
2. Ruling out a hypersensitivity reaction that may lead to multi-organ failure
3. Rapid strep test and symptomatic care if strep test is negative
4. Observation only, with further assessment if she worsens