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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The average adult has about 21 square feet of skin.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.
Individuals are never “cured” of addictions. Instead, they learn how to manage their disease to lead healthy, balanced lives.

