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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Adolescents often feel clumsy during puberty because during this time of development, their hands and feet grow faster than their arms and legs do. The body is therefore out of proportion. One out of five adolescents actually experiences growing pains during this period.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Approximately one in four people diagnosed with diabetes will develop foot problems. Of these, about one-third will require lower extremity amputation.