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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
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Recent studies have shown that the number of medication errors increases in relation to the number of orders that are verified per pharmacist, per work shift.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.