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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.
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Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.