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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Though the United States has largely rejected the metric system, it is used for currency, as in 100 pennies = 1 dollar. Previously, the British currency system was used, with measurements such as 12 pence to the shilling, and 20 shillings to the pound.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.