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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
About 3.2 billion people, nearly half the world population, are at risk for malaria. In 2015, there are about 214 million malaria cases and an estimated 438,000 malaria deaths.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
Medication errors are more common among seriously ill patients than with those with minor conditions.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.