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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Approximately one in four people diagnosed with diabetes will develop foot problems. Of these, about one-third will require lower extremity amputation.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.
The calories found in one piece of cherry cheesecake could light a 60-watt light bulb for 1.5 hours.