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Elderly adults are at greatest risk of stroke and myocardial infarction and have the most to gain from prophylaxis. Patients ages 60 to 80 years with blood pressures above 160/90 mm Hg should benefit from antihypertensive treatment.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
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Medication errors are three times higher among children and infants than with adults.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.