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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The longest a person has survived after a heart transplant is 24 years.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.